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Ketoconazole
(2 R,4 S )-(+)-ketoconazole (top) (2 S,4 R )-(−)-ketoconazole (bottom)
Clinical data
Pronunciation/ ˌ k iː t oʊ ˈ k oʊ n ə ˌ z oʊ l, - z ɒ l / [1] [2]
Trade namesNizoral, others
AHFS/Drugs.comMonograph
MedlinePlusa682816
License dataEU  EMA:  by INN, US   FDA: Ketoconazole
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationOral (tablets), topical (cream, shampoo, solution)
ATC codeJ02AB02 ( WHO ) D01AC08 ( WHO ) G01AF11 ( WHO )
Legal status
Legal statusUK: OTC US: OTC
Pharmacokinetic data
BioavailabilityOral: 37–97% [3]
Protein binding84 to 99%
MetabolismExtensive liver (predominantly oxidation, O -dealkylation)
MetabolitesN -deacetyl ketoconazole
Elimination half-lifeBiphasic
ExcretionBiliary (major) and renal [4]

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  • But if you've tried everything and your dandruff isn't improving, a quick visit to the dermatologist can help clear things up
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Nizoral, 4 reviews:

Comment №1 about product

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4 / 5 stars
Comment №2 about product

It should be used after you have determined the cause, either through ruling out with other treatments of doctors advice. The result is a build up of dead skin cells that form scales and large flakes and the cellular renewal process is sped up in response to try and be rid of the fungi. Though those reviews also fail to mention if it was even used in combination as recommended or if it was over used as a replacement to regular shampooing.


5 / 5 stars
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2 / 5 stars
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The result is a build up of dead skin cells that form scales and large flakes and the cellular renewal process is sped up in response to try and be rid of the fungi. Before using it, you should be aware that it is one of the shampoos with a specific target and will not likely work for your dandruff if its caused by something else.


5 / 5 stars
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