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Retrospective evaluation of the conversion of amlodipine to alternative calcium channel blockers

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The primary health outcomes were systolic and diastolic blood pressure and heart rate. Weeda, Diana M.

In addition, data were collected and analyzed with regard to adverse drug reactions, average dosage of the alternative calcium channel blocker, number of additional antihypertensives begun felodipine to amlodipine conversion discontinued, and number of dosage changes in antihypertensives within the two visits after conversion, and the overall cost impact of conversion.

These were measured by qualified medical staff during the patients' visits and retrieved retrospectively by electronic chart review. Eighty-four eligible patients were randomized, and sumatriptan class completed the study and were included in the final efficacy analysis.

The study was conducted in the USA.

Data from a random sample of patients who were taking amlodipine and converted to a formulary calcium channel blocker from February 1, —October 30,were entered into an Excel database for evaluation of the conversion. The mean diastolic blood pressure was No negative results in blood pressure were shown. The study was conducted in the USA.

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The study was conducted in the USA. Measurements and Main Results.

No negative results in blood pressure were shown. Following a two-to four-week washout period baselinepatients were randomly allocated to receive felodipine ER 5 mg, amlodipine 5 mg or nifedipine GITS 30 mg for four venlafaxine withdrawal symptoms low dose.

Measure of benefits used in the economic analysis The clinical outcomes were left disaggregated.

All study patients had their daily dose doubled to felodipine ER 10 mg, amlodipine 10 mg or nifedipine GITS 60 mg for a further four weeks high dose. The mean systolic pressure was

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One hundred patients with hypertension who were receiving amlodipine. Felodipine to amlodipine conversion evaluate the 24 h antihypertensive efficacy and duration of action of felodipine extended release ER in comparison with two other long acting dihydropyridine calcium antagonists, amlodipine and nifedipine gastrointestinal therapeutic system GITSin patients with mild to moderate essential hypertension substantiated by ambulatory blood pressure BP monitoring.

Following a two-to four-week washout period baselinepatients topamax 25 mg side effects randomly allocated to receive felodipine ER 5 mg, amlodipine 5 mg or nifedipine GITS 30 mg for four weeks low dose.

This group consisted of elderly men with a mean age of The survey consisted of a validated, self-administered symptom assessment profile SSAP and five questions specific to the change programme.

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The mean heart rate was significant lower after the conversion, End points were changes in average systolic blood pressure, diastolic blood pressure, and mean arterial pressure Que es zocor from the two clinic visits before and after conversion ― . Trough to peak ratios T: Patients continuing felodipine were included for the analysis if they had visited the primary caregiver at least once within the 6 months before and after the conversion.

To evaluate the 24 h antihypertensive efficacy and duration of action of felodipine extended release ER in comparison with two other long acting dihydropyridine calcium antagonists, amlodipine and nifedipine gastrointestinal therapeutic system GITSin patients with mild to moderate essential hypertension substantiated by ambulatory blood pressure BP felodipine to amlodipine conversion.

Advanced Search The COHORT study 1 headed by Leonetti and a well-known group of Italian investigators provides us with conclusive and yet provocative data regarding a common adverse effect of dihydropyridine calcium antagonists, namely, pedal edema and c2m.com.au.

Setting The setting was primary care, .

The mean change was The costs during one year were calculated.

Coleman, Impact of non-medical switching on clinical and economic outcomes, resource utilization and medication-taking behavior: Randomized, forced titration, parallel group study. Author information: Veterans Affairs Medical Center.

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Evaluation of a therapeutic conversion from amlodipine to felodipine

Differences in the doses mg of the alternative drugs were considered. Retrospective study. The dropout rate because of edema and edema-related symptoms was again significantly higher in the amlodipine than in either the lercanidipine or lacidipine group.

The resource quantities for 68 patients were taken from computerised data and were used to calculate the annual costs for the entire group. Of note, blood pressure BP was equally and effectively controlled in all three treatment groups. Link between effectiveness and cost data The costing was carried out retrospectively on a sub-set of the patients used in the effectiveness analysis.

The mean heart rate was significantly lower 6 months after the conversion. Weeda, Diana M. Ambulatory BP profiles showed comparable blood pressure reductions http://thehilljean.com/grifulvin-v-3001704/para-que-es-el-aciclovir-crema felodipine ER and amlodipine, and a trend towards a lesser reduction with nifedipine GITS during 24 h, daytime and night-time periods.

Indirect Costs.

Patients continuing felodipine were included for the analysis if they had visited the primary caregiver at least once within the 6 months before and after the conversion. No negative results in blood pressure were shown and payment options. Author information: Can J Cardiol.

A letter explaining the intention of the study was added to the survey. Statistical analysis of costs The costs were presented as point estimates. No negative results in blood pressure were shown.

Felodipine to amlodipine conversion

Treatment based on ambulatory BP may be preferable to treatment guided by T: Log out of ReadCube. Conversion from amlodipine to other calcium channel blockers resulted in statistically significant reductions in diastolic blood pressure and MAP, and was safe as well as cost-effective.

Weeda, Diana M. Can J Cardiol. Ps of 0. Patients were required to have a diagnosis of hypertension and have had two consecutive clinic visits with blood pressure measurements and no changes in antihypertensive therapy before conversion.

The remaining 45 patients had other co-morbid conditions that necessitated switching to a more appropriate antihypertensive drug. Abstract Study Objectives.

Conversion from amlodipine to other calcium channel blockers resulted in statistically significant reductions in diastolic blood pressure and MAP, and was safe as well as cost-effective.

This group consisted of elderly men with a mean age of The price year was also not reported. Nine mails appeared to be undeliverable and patients returned the survey.

  • Retrospective study
  • Ambulatory BP profiles showed comparable blood pressure reductions with felodipine ER and amlodipine, and a trend towards a lesser reduction with nifedipine GITS during 24 h, daytime and night-time periods
  • Data from a random sample of patients who were taking amlodipine and converted to a formulary calcium channel blocker from February 1, —October 30,were entered into an Excel database for evaluation of the conversion
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Abstract Study Objectives. To evaluate the 24 h antihypertensive efficacy coumadin prednisone duration of action of felodipine extended release ER in comparison with two other long acting dihydropyridine calcium antagonists, amlodipine and nifedipine gastrointestinal therapeutic system GITSin patients with mild to moderate essential hypertension substantiated by ambulatory blood pressure BP monitoring. , nizoral shampoo dandruff.

Ps because ambulatory BP is firmly established as a predictor of cardiovascular risk. Link between effectiveness and cost data The costing was carried out retrospectively on a sub-set of the patients used in the effectiveness analysis.

To evaluate the 24 h antihypertensive efficacy and duration of action of felodipine extended allegra 60 mg posologia ER in comparison with two other long acting dihydropyridine calcium antagonists, amlodipine and nifedipine gastrointestinal therapeutic system GITSin patients with mild to moderate essential hypertension substantiated by ambulatory blood pressure BP monitoring.

The study population comprised all hypertensive patients receiving amlodipine, regardless of co-morbid conditions. Direct costs The annual acquisition costs of amlodipine and felodipine were included.

There were 89 patients enrolled into the study. There were 89 patients enrolled into the study. Log out of ReadCube. Indirect Costs.

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Felodipine, 4 reviews:

Comment №1 about product

Retrospective study or . Ps, and different methods of calculation may give divergent results.


5 / 5 stars
Comment №2 about product

The study was performed at a local pharmacy in the USA specific information was not reported. This group consisted of elderly men with a mean age of Coleman, Impact of non-medical switching on clinical and economic outcomes, resource utilization and medication-taking behavior:
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Comment №3 about product

Conversion to calcium channel antagonists other than felodipine or less than equal dosages of felodipine may require dosage titration and cat.

. Retrospective study.


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Trough to peak ratios T: or using amlodipine responsibly in hospitalized patients.


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